PATENTS

 USPTO
Pat Num		TitleInventorsDate
110676518A4B2 nicotinic acetylcholine receptors with
reduced or increased nicotine sensitivity and transgenic mouse model for the same.		Caballero-Rivera; Daniel, Biaggi-
Labiosa; Nilza M, Aviles-Pagan; Emir, Lasalde-Dominicci; José A.		April 2016
29,650,627Site-directed RNA editingRosenthal; Joshua J. C., Montiel-Gonzalez; Maria FernandaMay 2017
310,106,572Supramolecular hacky sacks (SHS), method of synthesis and applications thereofRivera; Jose M, Negron; Luis MOct 2018
410,155,221High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition.Lasalde-Dominicci; Jose A., Quesada-Gonzalez;
Orestes, Rodriguez-Cordero; Josue, Baez-Pagan; Carlos		Dec 2018
510,358,475High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable compositionJose A. Lasalde-Dominicci, Orestes Quesada-Gonzalez, Josue Rodriguez-Cordero, Carlos Baez- PaganJuly 2019
610,597,462Anti-TLT-1 antibody and uses thereofWashington Anthony VMarch 2020
715/996,946High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable compositionJose A. Lasalde-DominicciApril 2022
April 1, 2022
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Jose A. Lasalde-Dominicci

U.S. Patent No: Pending

June 9, 2020
A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same)

Caballero Rivera D, Biaggi-Labiosa NM, Avilez-Pagan E, Lasalde-Dominicci JA

U.S. Patent No: 10,676,518

March 24, 2020
ANTI-TLT-1 ANTIBODY AND USES THEREOF

Valance-Washington A, Ferrer-Acosta Y, Morales J, Reyes-Baez F

U.S. Patent No: 10,597,462

July 23, 2019
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Lasalde-Dominicci; Jose A., Quesada-Gonzalez; Orestes, Rodriguez-Cordero, Josue, Baez-Pagan; Carlos

U. S. Patent No: 10, 358, 475

December 18, 2018
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Lasalde-Dominicci; José A., Quesada-González; Orestes, Rodríguez-Cordero, Josué, Báez-Pagan; Carlos

U.S. Patent No: 10,155,221

October 23, 2018
Supramolecular hacky sacks (SHS), method of synthesis and applications thereof

Rivera JM, Negrón LM

U.S. Patent No: 10,106,572

May 16, 2017
Site-directed RNA editing

Rosenthal JJC, Montiel-González MF

U.S. Patent No: 9,650,627

PUBLICATIONS

April 3, 2017
Assessing the Suitability of Cellulose-Nanodiamond Composite as a Multifunctional Biointerface Material for Bone Tissue Regeneration

Vega-Figueroa K, Santillán J, García C, González-Feliciano JA, Bello SA, Rodríguez YG, Ortiz-Quiles E, Nicolau E
ACS Biomater Sci Eng. 2017;3(6):960-968. DOI: 10.1021/acsbiomaterials.7b00026

February 24, 2017
Smart Release Nano-Formulation of Cytochrome C and Hyaluronic Acid Induces Apoptosis in Cancer Cells

Figueroa CM, Suárez BN, Molina AM, Fernández JC, Torres Z, Griebenow K
J. Nanomedicine Nanotechnol. 2017; 8 (1): 1–8. DOI: 10.4172/2157-7439.1000427

February 22, 2017
Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless

Alicea D, Perez M, Maldonado C, Dominicci-Cotto C, Marie B
J. Neurosci. Off. J. Soc. Neurosci. 2017; 37 (8): 2203–2215. DOI: 10.1523/JNEUROSCI.1375-
16.2017

February 20, 2017
Mutations Underlying Episodic Ataxia Type-1 Antagonize Kv1.1 RNA Editing

Ferrick-Kiddie EA, Rosenthal JJ, Ayers GD, Emeson RB
Sci Rep. 2017;7:41095. DOI: 10.1038/srep41095

December 1, 2016
A Survey of Energy Drink Consumption Patterns Among College Students at a Mostly Hispanic University.

Cabezas-Bou E, De León-Arbucias J, Matos-Vergara N, Álvarez-Bagnarol Y, Ortega-Guzmán J,
Narváez-Pérez K, Cruz-Bermúdez ND, Díaz-Ríos M
J. Caffeine Res. 2016; 6 (4): 154–162. DOI: 10.1089/jcr.2016.0011

November 1, 2016
Optic nerve injury upregulates retinoic acid signaling in the adult frog visual system.

Duprey-Díaz MV, Blagburn JM, Blanco RE
J. Chem. Neuroanat. 2016; 77 (Supplement C): 80–92. DOI: 10.1016/j.jchemneu.2016.05.008

November 1, 2016
The Multiple Waves of Cannabinoid 1 Receptor Signaling

Nogueras-Ortiz C, Yudowski GA
Mol. Pharmacol. 2016; 90 (5): 620–626. DOI: 10.1124/mol.116.104539

October 12, 2016
Alcohol Regulates BK Surface Expression via Wnt/β-Catenin Signaling

Velázquez-Marrero C, Burgos A, García JO, Palacio S, Marrero HG, Bernardo A, Pérez-Laspiur J,
Rivera-Oliver M, Seale G, Treistman SN
J. Neurosci. Off. J. Soc. Neurosci. 2016; 36 (41): 10625–10639. DOI: 10.1523/JNEUROSCI.0491-
16.2016

October 1, 2016
Cystatin B and HIV Regulate the STAT-1 Signaling Circuit in HIV-Infected and INF-β-Treated Human Macrophages

Rivera LE, Kraiselburd E, Meléndez LM
J. Neurovirol. 2016; 22 (5): 666–673. DOI: 10.1007/s13365-016-0443-6

September 19, 2016
Uncovering the Lipidic Basis for the Preparation of Functional Nicotinic Acetylcholine Receptor Detergent Complexes for Structural Studies

Quesada O, González-Freire C, Ferrer MC, Colón-Sáez JO, Fernández-García E, Mercado J, Dávila A, Morales R, Lasalde-Dominicci JA
Sci. Rep. 2016; 6 32766. DOI: 10.1038/srep32766

September 15, 2016
Tamoxifen Administration Immediately or 24 Hours after Spinal Cord Injury Improves Locomotor Recovery and Reduces Secondary Damage in Female Rats

Colón JM, Torrado AI, Cajigas Á, Santiago JM, Salgado IK, Arroyo Y, Miranda JD
J. Neurotrauma. 2016; 33 (18): 1696–1708. DOI: 10.1089/neu.2015.4111

September 9, 2016
Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury

Duprey-Díaz MV, Blagburn JM, Blanco RE
PloS One. 2016; 11 (9): e0162626. DOI: 10.1371/journal.pone.0162626

August 1, 2016
Heterogeneous Inhibition in Macroscopic Current Responses of Four Nicotinic Acetylcholine Receptor Subtypes by Cholesterol Enrichment.

Báez-Pagán CA, Del Hoyo-Rivera N, Quesada O, Otero-Cruz JD, Lasalde-Dominicci JA
J. Membr. Biol. 2016; 249 (4): 539–549. DOI: 10.1007/s00232-016-9896-z

August 1, 2016
Fatty Acid Binding Protein 5 Modulates Docosahexaenoic Acid-Induced Recovery in Rats Undergoing Spinal Cord Injury

Figueroa JD, Serrano-Illan M, Licero J, Cordero K, Miranda JD, De Leon M
J. Neurotrauma. 2016; 33 (15): 1436–1449. DOI: 10.1089/neu.2015.4186

August 1, 2016
Tamoxifen: an FDA approved drug with neuroprotective effects for spinal cord injury recovery.

Colón JM, Miranda JD
Neural Regen. Res. 2016; 11 (8): 1208–1211. DOI: 10.4103/1673-5374.189164

PRESENTATIONS

Some of the presentations sponsored by COBRE and NIEF cores could be observed in this file:

Presentations Sponsored by COBRE