PATENTS

June 9, 2020
A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same)

Caballero Rivera D, Biaggi-Labiosa NM, Avilez-Pagan E, Lasalde-Dominicci JA

U.S. Patent No: 10,676,518

March 24, 2020
ANTI-TLT-1 ANTIBODY AND USES THEREOF

Valance-Washington A, Ferrer-Acosta Y, Morales J, Reyes-Baez F

U.S. Patent No: 10,597,462

July 23, 2019
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Lasalde-Dominicci; Jose A., Quesada-Gonzalez; Orestes, Rodriguez-Cordero, Josue, Baez-Pagan; Carlos

U. S. Patent No: 10, 358, 475

October 23, 2018
Supramolecular hacky sacks (SHS), method of synthesis and applications thereof

Rivera JM, Negrón LM

U.S. Patent No: 10,106,572

May 16, 2017
Site-directed RNA editing

Rosenthal JJC, Montiel-González MF

U.S. Patent No: 9,650,627

PUBLICATIONS

January 27, 2021
A reversed phase HPLC method for the quantification of HIV gp145 glycoprotein levels from cell culture supernatants

González-Feliciano JA, Capó-Vélez CM, Akamine PY, Delgado-Vélez M, Almodóvar R, Pino I, Morell G, Eichinger D, Rivera JH, Lasalde-Dominicci JA, Baerga-Ortiz A,
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 27;1167:122562. doi:10.1016/j.jchromb.2021.122562.

August 24, 2020
Biophysical characterization dataset of native nicotinic acetylcholine receptor in lipid-like detergent complexes

Maldonado-Hernández R, Quesada O, Lasalde-Dominicci JA.
Data Brief. 2020 Aug 27;32:106230. doi: 10.1016/j.dib.2020.106230. eCollection 2020 Oct.

August 4, 2020
Sequential purification and characterization of Torpedo californica nAChR-DC supplemented with CHS for high-resolution crystallization studies

Maldonado-Hernández R, Quesada O, Colón-Sáez JO, Lasalde-Dominicci JA.
Anal Biochem. 2020 Dec 1;610:113887. doi: 10.1016/j.ab.2020.113887. Epub 2020 Aug 4.

June 19, 2020
A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity

González-Feliciano JA, Akamine P, Capó-Vélez CM, Delgado-Vélez M, Dussupt V, Krebs SJ, Wojna V, Polonis VR, Baerga-Ortiz A, Lasalde-Dominicci JA.
PLoS One. 2020 Jun 19;15(6):e0231679. doi: 10.1371/journal.pone.0231679. eCollection 2020.

April 1, 2019
GABA as a Neurotransmitter in Gastropod Molluscs

Miller MW
Biol Bull. 2019;236(2):144-156. DOI: 10.1086/701377.

March 26, 2019
An Immunohistochemical Analysis of Peptidergic Neurons Apparently Associated with Reproduction and Growth in Biomphalaria alexandrina

Acker MJ, Habib MR, Beach GA, Doyle JM, Miller MW, Croll RP
Gen Comp Endocrinol. 2019. pii: S0016-6480(18)30573-2. DOI: 10.1016/j.ygcen.2019.03.017

February 1, 2019
Adenosine A1-Dopamine D1 Receptor Heteromers Control the Excitability of the Spinal Motoneuron

Rivera-Oliver M, Moreno E, Álvarez-Bagnarol Y, Ayala-Santiago C, Cruz-Reyes N, Molina-Castro GC, Clemens S, Canela EI, Ferré S, Casadó V, Díaz-Ríos M
Mol Neurobiol. 2019;56(2):797-811. DOI: 10.1007/s12035-018-1120-y

January 1, 2019
Amphetamine enantiomers inhibit homomeric α7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

Garton DR, Ross SG, Maldonado-Hernández R, Quick M, Lasalde-Dominicci JA, Lizardi-Ortiz JE
Neuropharmacology. 2019;144:172-183. DOI: 10.1016/j.neuropharm.2018.10.032

December 26, 2018
A role for dopamine in the peripheral sensory processing of a gastropod mollusc

Brown JW, Schaub BM, Klusas BL, Tran AX, Duman AJ, Haney SJ, Boris AC, Flanagan MP, Delgado
N, Torres G, Rolón-Martínez S, Vaasjo LO, Miller MW, Gillette R
PLoS One. 2018;13(12):e0208891. DOI: 10.1371/journal.pone.0208891

December 6, 2018
Platelet-Derived TLT-1 Is a Prognostic Indicator in ALI/ARDS and Prevents Tissue Damage in the Lungs in a Mouse Model

Morales-Ortíz J, Deal V, Reyes F, Maldonado-Martínez G, Ledesma N, Staback F, Croft C,
Pacheco A, Ortiz-Zuazaga H, Yost CC, Rowley JW, Madera B, John AS, Chen J, Lopez J, Rondina
MT, Hunter R, Gibson A, Washington AV
Blood. 2018;132(23):2495-2505. DOI: 10.1182/blood-2018-03-841593

December 1, 2018
New Developments on the Adenosine Mechanisms of the Central Effects of Caffeine and their Implications for Neuropsychiatric Disorders

Ferré S, Díaz-Ríos M, Salamone JD, Prediger RD
J Caffeine Adenosine Res. 2018;8(4):121-131. DOI: 10.1089/caff.2018.0017

October 1, 2018
Nicotinic Acetylcholine Receptors in HIV: Possible Roles during HAND and Inflammation

Capó-Vélez CM, Delgado-Vélez M, Báez-Pagán CA, Lasalde-Dominicci JA
Cell Mol Neurobiol. 2018; 38(7):1335-1348. DOI: 10.1007/s10571-018-0603-8

August 1, 2018
GABA-Like Immunoreactivity in Biomphalaria: Colocalization with Tyrosine Hydroxylase-Like Immunoreactivity in the Feeding Motor Systems of Panpulmonate Snails

Vaasjo LO, Quintana AM, Habib MR, Mendez de Jesus PA, Croll RP, Miller MW
J Comp Neurol. 2018;526(11):1790-1805. DOI: 10.1002/cne.24448

July 15, 2018
T1- and T2-Weighted Magnetic Resonance Dual Contrast by Single Core Truncated Cubic Iron Oxide Nanoparticles with Abrupt Cellular Internalization and Immune Evasion

Thapa B, Diaz-Diestra D, Santiago-Medina C, Kumar N, Tu K, Beltran-Huarac J, Jadwisienczak
WM, Weiner BR, Morell G
ACS Appl Bio Mater. 2018;1(1):79-89. DOI: 10.1021/acsabm.8b00016

May 16, 2018
The Cholinergic Anti-Inflammatory Response and the Role of Macrophages in HIV-Induced Inflammation

Delgado-Vélez M, Lasalde-Dominicci JA
Int J Mol Sci. 2018;19(5). pii: E1473. DOI: 10.3390/ijms19051473