PATENTS

February 26, 2020
A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same)

Caballero Rivera D, Biaggi-Labiosa NM, Avilez-Pagan E, Lasalde-Dominicci JA

U.S. Patent No:  Pending

August 1, 2019
ANTI-TLT-1 ANTIBODY AND USES THEREOF

A. Valance Washington

Appl. No.: 16/242,995
Docket: UPR-14230

July 23, 2019
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Lasalde-Dominicci; Jose A., Quesada-Gonzalez; Orestes, Rodriguez-Cordero, Josue, Baez-Pagan; Carlos

U. S. Patent No: 10, 358, 475

October 23, 2018
Supramolecular hacky sacks (SHS), method of synthesis and applications thereof

Rivera JM, Negrón LM

U.S. Patent No: 10,106,572

May 16, 2017
Site-directed RNA editing

Rosenthal JJC, Montiel-González MF

U.S. Patent No: 9,650,627

PUBLICATIONS

April 1, 2019
GABA as a Neurotransmitter in Gastropod Molluscs

Miller MW
Biol Bull. 2019;236(2):144-156. DOI: 10.1086/701377.

March 26, 2019
An Immunohistochemical Analysis of Peptidergic Neurons Apparently Associated with Reproduction and Growth in Biomphalaria alexandrina

Acker MJ, Habib MR, Beach GA, Doyle JM, Miller MW, Croll RP
Gen Comp Endocrinol. 2019. pii: S0016-6480(18)30573-2. DOI: 10.1016/j.ygcen.2019.03.017

February 1, 2019
Adenosine A1-Dopamine D1 Receptor Heteromers Control the Excitability of the Spinal Motoneuron

Rivera-Oliver M, Moreno E, Álvarez-Bagnarol Y, Ayala-Santiago C, Cruz-Reyes N, Molina-Castro GC, Clemens S, Canela EI, Ferré S, Casadó V, Díaz-Ríos M
Mol Neurobiol. 2019;56(2):797-811. DOI: 10.1007/s12035-018-1120-y

January 1, 2019
Amphetamine enantiomers inhibit homomeric α7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

Garton DR, Ross SG, Maldonado-Hernández R, Quick M, Lasalde-Dominicci JA, Lizardi-Ortiz JE
Neuropharmacology. 2019;144:172-183. DOI: 10.1016/j.neuropharm.2018.10.032

December 26, 2018
A role for dopamine in the peripheral sensory processing of a gastropod mollusc

Brown JW, Schaub BM, Klusas BL, Tran AX, Duman AJ, Haney SJ, Boris AC, Flanagan MP, Delgado
N, Torres G, Rolón-Martínez S, Vaasjo LO, Miller MW, Gillette R
PLoS One. 2018;13(12):e0208891. DOI: 10.1371/journal.pone.0208891

December 6, 2018
Platelet-Derived TLT-1 Is a Prognostic Indicator in ALI/ARDS and Prevents Tissue Damage in the Lungs in a Mouse Model

Morales-Ortíz J, Deal V, Reyes F, Maldonado-Martínez G, Ledesma N, Staback F, Croft C,
Pacheco A, Ortiz-Zuazaga H, Yost CC, Rowley JW, Madera B, John AS, Chen J, Lopez J, Rondina
MT, Hunter R, Gibson A, Washington AV
Blood. 2018;132(23):2495-2505. DOI: 10.1182/blood-2018-03-841593

December 1, 2018
New Developments on the Adenosine Mechanisms of the Central Effects of Caffeine and their Implications for Neuropsychiatric Disorders

Ferré S, Díaz-Ríos M, Salamone JD, Prediger RD
J Caffeine Adenosine Res. 2018;8(4):121-131. DOI: 10.1089/caff.2018.0017

October 1, 2018
Nicotinic Acetylcholine Receptors in HIV: Possible Roles during HAND and Inflammation

Capó-Vélez CM, Delgado-Vélez M, Báez-Pagán CA, Lasalde-Dominicci JA
Cell Mol Neurobiol. 2018; 38(7):1335-1348. DOI: 10.1007/s10571-018-0603-8

August 1, 2018
GABA-Like Immunoreactivity in Biomphalaria: Colocalization with Tyrosine Hydroxylase-Like Immunoreactivity in the Feeding Motor Systems of Panpulmonate Snails

Vaasjo LO, Quintana AM, Habib MR, Mendez de Jesus PA, Croll RP, Miller MW
J Comp Neurol. 2018;526(11):1790-1805. DOI: 10.1002/cne.24448

July 15, 2018
T1- and T2-Weighted Magnetic Resonance Dual Contrast by Single Core Truncated Cubic Iron Oxide Nanoparticles with Abrupt Cellular Internalization and Immune Evasion

Thapa B, Diaz-Diestra D, Santiago-Medina C, Kumar N, Tu K, Beltran-Huarac J, Jadwisienczak
WM, Weiner BR, Morell G
ACS Appl Bio Mater. 2018;1(1):79-89. DOI: 10.1021/acsabm.8b00016

May 16, 2018
The Cholinergic Anti-Inflammatory Response and the Role of Macrophages in HIV-Induced Inflammation

Delgado-Vélez M, Lasalde-Dominicci JA
Int J Mol Sci. 2018;19(5). pii: E1473. DOI: 10.3390/ijms19051473

April 12, 2018
Inducing Cell Death In Vitro in Cancer Cells by Targeted Delivery of Cytochrome C via a Transferrin Conjugate

Saxena M, Delgado Y, Sharma RK, Sharma S, Guzmán SLPL, Tinoco AD, Griebenow K
PLoS One. 2018;13(4):e0195542. DOI: 10.1371/journal.pone.0195542

April 1, 2018
The Characterization of Monoclonal Antibodies to Mouse TLT-1 Suggests That TLT-1 Plays a Role in Wound Healing

Barbara M, Morales-Ortíz J, Díaz-Díaz LM, Hernandez-Matias L, Barreto-Vázquez D, Menéndez-Pérez J,Rodríguez-Cordero JA,Villalobos-Santos JC,Santiago-Rivera E, Rivera-Dompenciel A,Lozada-Delgado EL, Kuchibhotla M, Carrasquillo-Carrión K, Roche-Lima A, and Washington AV. Monoclon Antib

Immunodiagn Immunother. 2018 Apr 1; 37(2): 78–86. DOI: 10.1089/mab.2017.0063

March 28, 2018
TLT-1-Controls Early Thrombus Formation and Stability by Facilitating AIIBB3 Outside-In Signaling in Mice

Morales-Ortíz J, Reyes F, Santiago O, Rivera L, Ledesma N, Manne B, Madera B, Rondina MT and Washington AV. Int J Adv

Res (Indore). 2018 Mar;6(3):1143-1149. DOI: 10.21474/IJAR01/7469.

January 29, 2018
The Alpha7-Nicotinic Receptor Contributes to GP120-Induced Neurotoxicity: Implications in HIV-Associated Neurocognitive Disorders

Capó-Vélez CM, Morales-Vargas B, García-González A, Grajales-Reyes JG, Delgado-Vélez M, Madera B, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA
Sci Rep. 2018;8(1):1829. doi: 10.1038/s41598-018-20271-x