PATENTS

February 26, 2020
A4B2 nicotinic acetylcholine receptors with reduced or increased nicotine sensitivity and transgenic mouse model for the same)

Caballero Rivera D, Biaggi-Labiosa NM, Avilez-Pagan E, Lasalde-Dominicci JA

U.S. Patent No:  Pending

August 1, 2019
ANTI-TLT-1 ANTIBODY AND USES THEREOF

A. Valance Washington

Appl. No.: 16/242,995
Docket: UPR-14230

July 23, 2019
High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition

Lasalde-Dominicci; Jose A., Quesada-Gonzalez; Orestes, Rodriguez-Cordero, Josue, Baez-Pagan; Carlos

U. S. Patent No: 10, 358, 475

October 23, 2018
Supramolecular hacky sacks (SHS), method of synthesis and applications thereof

Rivera JM, Negrón LM

U.S. Patent No: 10,106,572

May 16, 2017
Site-directed RNA editing

Rosenthal JJC, Montiel-González MF

U.S. Patent No: 9,650,627

PUBLICATIONS

January 8, 2018
Pivotal Role of Adenosine Neurotransmission in Restless Legs Syndrome

Ferré S, Quiroz C, Guitart X, Rea W, Seyedian A, Moreno E, Casadó-Anguera V, Díaz-Ríos M,
Casadó V, Clemens S, Allen RP, Earley CJ, García-Borreguero D
Front Neurosci. 2018;11:722. DOI: 10.3389/fnins.2017.00722

January 1, 2018
Continuous Tamoxifen Delivery Improves Locomotor Recovery 6h After Spinal Cord Injury by Neuronal and Glial Mechanisms in Male Rats

Colón JM, González PA, Cajigas Á, Maldonado WI, Torrado AI, Santiago JM, Salgado IK, Miranda JD
Exp Neurol. 2018;299(Pt A):109-121. DOI: 10.1016/j.expneurol.2017.10.006

November 15, 2017
Retromer Stops Beta-Arrestin 1-Mediated Signaling from Internalized Cannabinoid 2 Receptors

Nogueras-Ortiz C, Roman-Vendrell C, Mateo-Semidey GE, Liao YH, Kendall DA, Yudowski GA
Mol Biol Cell. 2017;28(24):3554-3561. DOI: 10.1091/mbc.E17-03-0198

September 9, 2017
Simultaneous Activation of Parallel Sensory Pathways Promotes a Grooming Sequence in Drosophila

Hampel S, McKellar CE, Simpson JH, Seeds AM
eLife. 2017; 6DOI: 10.7554/eLife.28804

July 17, 2017
Expanding the Therapeutic Potential of the Iron Chelator Deferasirox in the Development of Aqueous Stable Ti(IV) Anticancer Complexes.

Loza-Rosas SA, Vázquez-Salgado AM, Rivero KI, Negrón LJ, Delgado Y, Benjamín-Rivera JA,
Vázquez-Maldonado AL, Parks TB, Munet-Colón C, Tinoco AD.
Inorg Chem. 2017;56(14):7788-7802. DOI: 10.1021/acs.inorgchem.7b00542.

April 3, 2017
Assessing the Suitability of Cellulose-Nanodiamond Composite as a Multifunctional Biointerface Material for Bone Tissue Regeneration

Vega-Figueroa K, Santillán J, García C, González-Feliciano JA, Bello SA, Rodríguez YG, Ortiz-Quiles E, Nicolau E
ACS Biomater Sci Eng. 2017;3(6):960-968. DOI: 10.1021/acsbiomaterials.7b00026

February 24, 2017
Smart Release Nano-Formulation of Cytochrome C and Hyaluronic Acid Induces Apoptosis in Cancer Cells

Figueroa CM, Suárez BN, Molina AM, Fernández JC, Torres Z, Griebenow K
J. Nanomedicine Nanotechnol. 2017; 8 (1): 1–8. DOI: 10.4172/2157-7439.1000427

February 22, 2017
Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless

Alicea D, Perez M, Maldonado C, Dominicci-Cotto C, Marie B
J. Neurosci. Off. J. Soc. Neurosci. 2017; 37 (8): 2203–2215. DOI: 10.1523/JNEUROSCI.1375-
16.2017

February 20, 2017
Mutations Underlying Episodic Ataxia Type-1 Antagonize Kv1.1 RNA Editing

Ferrick-Kiddie EA, Rosenthal JJ, Ayers GD, Emeson RB
Sci Rep. 2017;7:41095. DOI: 10.1038/srep41095

December 1, 2016
A Survey of Energy Drink Consumption Patterns Among College Students at a Mostly Hispanic University.

Cabezas-Bou E, De León-Arbucias J, Matos-Vergara N, Álvarez-Bagnarol Y, Ortega-Guzmán J,
Narváez-Pérez K, Cruz-Bermúdez ND, Díaz-Ríos M
J. Caffeine Res. 2016; 6 (4): 154–162. DOI: 10.1089/jcr.2016.0011

November 1, 2016
Optic nerve injury upregulates retinoic acid signaling in the adult frog visual system.

Duprey-Díaz MV, Blagburn JM, Blanco RE
J. Chem. Neuroanat. 2016; 77 (Supplement C): 80–92. DOI: 10.1016/j.jchemneu.2016.05.008

November 1, 2016
The Multiple Waves of Cannabinoid 1 Receptor Signaling

Nogueras-Ortiz C, Yudowski GA
Mol. Pharmacol. 2016; 90 (5): 620–626. DOI: 10.1124/mol.116.104539

October 12, 2016
Alcohol Regulates BK Surface Expression via Wnt/β-Catenin Signaling

Velázquez-Marrero C, Burgos A, García JO, Palacio S, Marrero HG, Bernardo A, Pérez-Laspiur J,
Rivera-Oliver M, Seale G, Treistman SN
J. Neurosci. Off. J. Soc. Neurosci. 2016; 36 (41): 10625–10639. DOI: 10.1523/JNEUROSCI.0491-
16.2016

October 1, 2016
Cystatin B and HIV Regulate the STAT-1 Signaling Circuit in HIV-Infected and INF-β-Treated Human Macrophages

Rivera LE, Kraiselburd E, Meléndez LM
J. Neurovirol. 2016; 22 (5): 666–673. DOI: 10.1007/s13365-016-0443-6

September 19, 2016
Uncovering the Lipidic Basis for the Preparation of Functional Nicotinic Acetylcholine Receptor Detergent Complexes for Structural Studies

Quesada O, González-Freire C, Ferrer MC, Colón-Sáez JO, Fernández-García E, Mercado J, Dávila A, Morales R, Lasalde-Dominicci JA
Sci. Rep. 2016; 6 32766. DOI: 10.1038/srep32766